Potion of cure mutation

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Obsolete: This article refers to an aspect of the game which has been removed. It is retained for historical reference only.
A potion which removes some or all of any mutations which may be afflicting you.
Type Potion
Name Potion of Cure Mutation
Icon Potion of cure mutation.png
Quaffing a potion of cure mutation will immediately remove 0-7 random mutations (heavily weighted toward 3-5) from your character. They are one of the rarer potions to find randomly, and are expensive when found in shops, but they are the only reliable means of removing undesirable mutations for characters who don't worship Zin or Jiyva. Most characters who enter the Slime Pits or the Realm of Zot will have need of them.

Be aware that potions of cure mutation function indiscriminately, removing good mutations as well as bad.

However, any mutation that is inherent to your species (e.g., a draconian's scales, a naga's slow movement speed, demonspawn mutations) will never be affected. Also, rank 2 of the Mutation Resistance mutation causes it to fail 50% of the time, while rank 3 renders it completely ineffective.

When drunk, the potion has a "very clean taste."

# Removed 0 1 2 3 4 5 6 7
Probability (%) 0.05 1.0 6.3 19.8 32.2 27.4 11.4 1.8


  • Being without a potion of cure mutation when you need one is extremely frustrating, as is suddenly eradicating several good mutations by accident. Try to avoid drinking unidentified potions until you've ID'd this one.
  • As a desperate long-shot, one can quaff potions of mutation in an attempt to reverse the effects of one's current bad mutations. While this may result in you becoming even worse off than you were at the start, characters with many bad mutations and few good ones are much more likely to wind up losing some of the bad and gaining some good.


Potions of cure mutation and potions of beneficial mutation were merged into potions of mutation in 0.20.

Prior to 0.18, potions of cure mutation were slightly less common.

AmbrosiaAttractionBerserk rageBrillianceCancellationCuringDegenerationExperienceFlightHasteHeal woundsInvisibilityLignificationMagicMightMutationResistance